Because FSTL-1 is important in CIA and autoimmune arthritides, and Lyme arthritis shares similarities with CIA, we hypothesized that FSTL-1 may be an important mediator of Lyme arthritis. HHS Lyme Disease has multiple symptoms including muscle aches, joint pain, fever, chills, impaired memory and facial paralysis. 2009 Dec;60(12):3831-40. doi: 10.1002/art.25005. 2020 Apr 15;201(8):934-945. doi: 10.1164/rccm.201905-0973OC.
(A) DBA/1WT (squares) and FSTL-1 hypomorph mice (circles) were infected with 10, FSTL-1 influences inflammatory cytokine production in vivo.
Arthritis; Borrelia burgdorferi; FSTL-1; Lyme disease; Mouse model; humoral immunity. The number of cases doubled in the ’90s, but growth has since slowly plateaued at the national level. The amendment was introduced by New Jersey Rep. Chris Smith who said he was inspired to write it by "a number of books and articles suggesting that significant research had been done at US government facilities including Fort Detrick, Maryland, and Plum Island, New York, to turn ticks and other insects into bioweapons. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Clipboard, Search History, and several other advanced features are temporarily unavailable. Access this article for 1 day for:£30 / $37 / €33 (excludes VAT).
The role of eicosanoids in experimental Lyme arthritis. eCollection 2014. Follistatin-like protein 1 (FSTL-1) has recently been described as a critical mediator of CIA and a marker of disease activity. Get the latest research from NIH: https://www.nih.gov/coronavirus. Arthritis Rheum. ", During the amendment's debate, Smith said Lyme disease and other tick-borne diseases were "exploding" in the US and that "Americans have a right to know whether any of this is true. Curr Opin Rheumatol. BB0744 Affects Tissue Tropism and Spatial Distribution of Borrelia burgdorferi. Lyme disease has surged in some US states, such as Wisconsin. ", "If true, what were the parameters of the program? Clin Case Rep. 2018 May 2;6(6):1166-1171. doi: 10.1002/ccr3.1556. 2015 Sep;83(9):3693-703. doi: 10.1128/IAI.00828-15. Wager B, Shaw DK, Groshong AM, Blevins JS, Skare JT. ELISA plates coated…, FSTL-1 is critical to Borrelia burgdorferi antigen recognition.
(A).…, FSTL-1 mediates the development of Lyme arthritis. NIH eCollection 2014.
The US House of Representatives has ordered the Pentagon’s inspector general to conduct a review of whether the defence department “experimented with ticks and other insects regarding use as biological weapons between 1950 and 1975.”1. The mainstream “origin story” of Lyme disease in the United States goes like this: In the 1970s, a mysterious ailment afflicted a group of people in and around Lyme, Connecticut.
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